My research is focused on: developing new trial endpoints for researchers to assess the efficacy of interventions, informing clinicians making individualised care decisions, and enabling/empowering people with Multiple sclerosis. My Thesis explores the Margin of Stability of standing balance[1] as a measure of balance in people with Multiple Sclerosis, and how measures of balance can best be recorded using smartphone sensors. My PhD project has close industrial co-supervision and sponsorship from F. Hoffman La Roche.

In addition to the main Research project, I have completed rotations/side projects with my industrial partner company developing a game to communicate the process and tools of computational drug discovery to students, and modelling disease to inform supply chain decision-making. I completed a rotation with another industrial partner and Diamond Light source, developing a system for automated robotic organic synthesis of small molecules for crystallography as part of a rapid response drug discovery pipeline.

[1] Simpson, O.F., Stanev, D., Pitt-Francis, J., Zanon, M., Rinderknecht, M.D. and Zavatsky, A.B., 2026. Standing margin of stability as a measure of balance for people with multiple sclerosis. Clinical Biomechanics, p.106696. (doi.org/10.1016/j.clinbiomech.2025.106696)